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. 2021 Jul 23;13:1759720X211022533. doi: 10.1177/1759720X211022533

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© The Author(s), 2021

This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — Venn diagram showing the overlap of antibodies against ac-lysine, ac-lysine.inv, and ac-ornithine in patients with rheumatic diseases and healthy subjects indicating the respective percentages of patients testing positive for individual AAPA and combinations thereof. (a) Early RA (n = 120). (b) Established RA (n = 195). (c) Healthy controls (n = 99). (d) Spondyloarthritis (n = 50). (e) Other inflammatory rheumatic diseases (SLE, n = 49; pSS, n = 88; GPA = 14; myositis, n = 15).

AAPA, anti-acetylated peptide antibodies; GPA, granulomatosis with polyangiitis; pSS, primary Sjögren’s syndrome; RA, rheumatoid arthritis; SLE, systemic lupus erythematosus.