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. 2021 Sep 14;20:15330338211039126. doi: 10.1177/15330338211039126

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© The Author(s) 2021

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — Alternative splicing analysis by ATP5A1-OE. (a) Bar plot showing the ratio of spliced reads in ATP5A1 and control samples (Student's t-test, * P < 0.05). (b) Bar plot showing the number of RASEs by classifying them into ten types. (c) Venn diagram showing the overlapping genes between the DEGs and RASGs. (d) Bubble plot showing the top ten enriched GO BP terms for RASGs. Terms related to cancer pathways are labeled in red. (e) Bubble plot showing the top ten enriched KEGG pathways for RASGs. Terms related to cancer pathways are labeled in red.

Abbreviations: OE, overexpression; RASEs, regulated ASEs; DEG, differentially expressed gene; RASGs, regulated alternative splicing genes; GO, gene ontology; BP, biological pathway.