Table 2.
Genetic subgroup characteristics to address exploratory aim.
| ADNP (N = 19) | CHD8 (N = 23) | DYRK1A (N = 23) | ||||||
|---|---|---|---|---|---|---|---|---|
| n | % | n | % | n | % | Group differences | Description | |
| Male | 11 | 57.89% | 14 | 63.64% | 15 | 65.22% | χ2(1) = .26, p = .88 | |
| Female | 8 | 42.11% | 8 | 36.36% | 8 | 34.78% | ||
| ASD Diagnosisa | 10 | 52.63% | 20 | 90.91% | 20 | 86.96% | χ2(1) = 11.0, p = .026 | ADNP<(DYRK1A, CHD8) |
| ID Diagnosisa | 19 | 100.00% | 11 | 50.00% | 19 | 82.61% | χ2(1) = 14.9, p = .006 | CHD8<(ADNP, DYRK1A) |
| Mean | SD | Mean | SD | Mean | SD | Group differences | Description | |
| Age (years) | 8.10 | 3.81 | 10.28 | 5.21 | 10.99 | 6.35 | F(1,61) = 1.63 p = .20 | |
| Age range (years) | 3–17 | 4–20 | 4–24 | |||||
| VIQ | 28.44 | 21.44 | 51.40 | 35.91 | 43.22 | 32.46 | F(1, 56) = 2.44, p = .51 | |
| NVIQ | 27.13 | 19.10 | 57.55 | 32.89 | 43.78 | 27.04 | F(1, 56) = 5.48, p = .007 | ADNP<CHD8 |
| Internalization | 57.07 | 9.51 | 62.21 | 8.81 | 57.00 | 11.08 | F(1, 44) = 1.61, p = .21 | |
| Externalization | 60.60 | 8.72 | 50.79 | 12.22 | 52.08 | 9.80 | F(1,44) = 4.01, p = .025 | ADNP<CHD8 |
a
Diagnoses unclear for 1 ADNP participant due to remote only participation.