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. 2021 Sep 6;134(17):jcs258428. doi: 10.1242/jcs.258428

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© 2021. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 6. — ATX-2 is required to maintain nuclear structure. (A–H) Representative microscope images of worms expressing LMN-1::GFP fed with either EV (A–D) or atx-2(RNAi) post-hatching (E–H), at day 1 (A,E), day 3 (B,F), day 5 (C,G) and day 7 (D,H) of adulthood. (I) Relative distribution of the three different classes grading the nuclear morphology changes in LMN-1::GFP expressing worms fed with atx-2 (RNAi) or EV at days 1, 3, 5 and 7 of adulthood. n(D1)=228 nuclei, n(D3)=267 nuclei, n(D5)=283 nuclei, n(D7)=262 nuclei. Error bars in all graphs represent mean±s.e.m. ***P<0.0001 (Fisher exact probability test).