Table 2. GRK5 genotype and allele frequencies in the HF patient cohort.
| Genotype | HF patients (n=584), n (%) | HF patients (β-blockers) (n=304), n (%) | HF patients (non-β-blockers) (n=280), n (%) | p-value |
|---|---|---|---|---|
| AA | 493 (84) | 244(80) | 249(89) | 0.011 |
| AT | 85 (15) | 57 (19) | 28 (10) | |
| TT | 6 (1) | 3 (1) | 3 (1) | |
| Allele | 0.07 | |||
| A | 535 (91.6) | 273 (90) | 263 (94) | |
| T | 49 (8.4) | 31 (10) | 17 (6) |
Results were expressed as n (%) for genotype and allele distribution. χ2 test was significant for genotype frequency and not significant for allele frequency between β-blocker group and the non-β-blocker group.