ROC curves for plasma levels of kisspeptin, βhCG, and kisspeptin and βhCG for gestational weeks <eight weeks (left panel) and eight or more weeks (right panel). For the left panel, the AUCs are 78.4% (kisspeptin), 79.5% (βhCG), and 79.7% (both factors). For the right panel, the AUCs are 90.9% (kisspeptin), 79.6% (βhCG), and 92.3% (both factors). Gestational ages were determined by LMP. AUC = area under the curve; βhCG = beta human chorionic gonadotropin; KP = kisspeptin; LMP = last menstrual period; ROC = receiver-operating characteristic.