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. 2019 Oct 25;173(2):244–254. doi: 10.1093/toxsci/kfz222

Figure 7.

Figure 7.

Ald1a1 and Adh1 do not significantly increase in a rat model of cholestasis. Rats were subjected to either bile duct ligation (BDL) or sham surgery (Sham), then allowed to recover. Blood was collected 21 days after surgery. A, Serum ALT activity. B, H&E-stained liver sections. C, Immunoblots for Aldh1a1 and Adh1in serum. D, Detection of both mouse (M) and rat (R) Aldh1a1 and Adh1 using the same antibody. Total protein is also displayed. Data expressed as mean ± SE for n = 3 rats per group. *p < .05 versus Sham.