Table 2. Outcomes of conventional treatment versus over-the-scope clip (OTSC) as first-line treatment.
| Standard therapy group (n = 47) | OTSC group (n = 21) | NNT/NNH | P value | |
| Intra-procedural hemostasis | 39 (83.0) | 20 (95.2) | NNT: 9 | 0.256 |
| 7-day rebleeding | 10 (21.3) | 2 (9.5) | NNT: 9 | 0.317 |
| Repeat endoscopy | 7 (14.9) | 4 (19.1) | NNH: 25 | 0.727 |
| Endoscopic intervention on repeat endoscopy | 5 (10.6) | 1 (4.8) | – | 0.658 |
| Vascular embolization performed | 6 (12.8) | 3 (14.3) | – | 1.000 |
| Procedure duration | 23 [14–32] | 16 [14–21] | – | 0.002 |
| Cost 1 | 398 [242–596] | 438 [438–482] | – | 0.203 |
| Length of hospital stay | 5 [4–11] | 5 [4–8] | – | 0.864 |
| In-hospital mortality | 2 (4.3) | 0 (0.0) | NNT: 23 | 1.000 |
| 30-day readmission 2 | 2 (4.4) | 0 (0.0) | NNT: 24 | 1.000 |
OTSC, over-the-scope clip; NNT, number needed to treat; NNH, number needed to harm.
1
Costs epinephrine vial $15, bipolar probe $198, injection needle $29, through-the-scope clip $199, and OTSC $438.
2
Analysis only includes patient discharged alive.