Table 4. Cox regression analyses between scores or fecal calprotectin (independent variables) and main outcomes (dependent variables).

	CE-CD		Lewis score		CECDAI		FCP
	Hazard ratio (95 % CI)	P value	Hazard ratio (95 % CI)	P value	Hazard ratio (95 % CI)	P value	Hazard ratio (95 % CI)	P value
Surgery	1.014 (0.977–1.053)	0.449	1.001 (1.000–1.001)	0.027	1.042 (0.993–1.092)	0.093	1.00003 (0.999–1.0002)	0.646
Hospitalization	1.061 (1.048–1.075)	< 0.001	1.001 (1.000–1.001)	< 0.001	1.096 (1.076–1-117)	< 0.001	1.0003 (1.0002–1.0004)	< 0.001
Treatment escalation	1.062 (1.050–1.074)	< 0.001	1.001 (1.000–1.001)	< 0.001	1.093 (1.076–1.112)	< 0.001	1.0003 (1.0002–1.0004)	< 0.001
Steroids	1.082 (1.007–1.096)	< 0.001	1.001 (1.000–1.001)	< 0.001	1.112 (1.093–1.132)	< 0.001	1.0004 (1.0003–1.0005)	< 0.001
Clinical relapse	1.064 (1.052–1.076)	< 0.001	1.001 (1.000–1.001)	< 0.001	1.102 (1.084–1.121)	< 0.001	1.0003 (1.0002–1.0004)	< 0.001
Endoscopic relapse	1.060 (1.048–1.072)	< 0.001	1.001 (1.000–1.001)	< 0.001	1.099 (1.080–1.118)	< 0.001	1.0003 (1.0002–1.0004)	< 0.001