Figure 3.

PIH reduced neuronal death and improved neurological function recovery in ICH mice. (a) Experimental design time axis. (b) Modified neurological severity scores (mNSS) and (c) rotarod test were performed to evaluate from day 1 to day 14 post-ICH to evaluate neural function recovery. n = 12. (d, e) Immunofluorescence staining was used to detect the survival neurons around the hematoma. NeuN represents neuronal cells (green), DAPI is nucleus (blue) (F = 213.3, n = 5). The data are expressed as average ± SD, scale = 100 μm. ^∗P < 0.05, ^∗∗P < 0.01, ^∗∗∗P < 0.001; ns: not significant.