Table 1.
Proportion of the secondary structural elements calculated by deconvolution of far-UV CD spectra of RBD and its mutants using BeStSel software (45)
| RBD variant | Secondary structure (%) |
||||
|---|---|---|---|---|---|
| Helix | Antiparallel | Parallel | Turn | Others | |
| Wildtype | 13.7 | 25.0 | 0.0 | 13.9 | 47.3 |
| K417N | 12.8 | 17.9 | 4.4 | 14.1 | 50.7 |
| Y453F | 15.3 | 19.2 | 1.5 | 13.9 | 50.2 |
| S477N | 13.5 | 22.0 | 2.0 | 13.2 | 49.3 |
| T478I | 13.8 | 17.8 | 3.2 | 13.3 | 51.9 |
| E484K | 15.7 | 16.3 | 4.0 | 13.4 | 50.6 |
| S494P | 14.1 | 21.4 | 2.1 | 13.3 | 49.1 |
| N501Y | 11.4 | 22.9 | 2.8 | 13.0 | 49.9 |
| K417T/E484K/N501Y | 10.4 | 24.3 | 2.9 | 13.1 | 49.3 |