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Exogenous FGF21 rescues FGF21 knockdown-mediated ferroptosis.
Fgf21 was knocked down in the primary hepatocytes, followed by mock treatment or treatment with 200 ng/ml recombinant FGF21 for 24 h (A to E) Levels of LIP, ROS, GSH, MDA and C11-BODIPY in the cells (n = 4). (F) Iron metabolism and ferroptosis related proteins expression in the cells (n = 3).
