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. 2021 Sep 16;12:5356. doi: 10.1038/s41467-021-25553-z

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Analysis of PRC1 mRNA expression in 50 EwS and 929 normal tissues (comprising 71 normal tissue types). Data are represented as box plots. Horizontal bars indicate median expression levels, boxes the interquartile range, and whiskers the 10th and 90th percentile. Two-sided Mantel-Haenszel test. b Kaplan-Meier survival analysis of 196 EwS patients stratified by thirds of PRC1 mRNA expression (Low, Moderate, High). Two-sided Mantel-Haenszel test. c Left: IHC staining of a TMA comprising 144 EwS tumors for PRC1. Scale bar = 100 µm. Right: Kaplan-Meier analysis of overall survival of 144 EwS patients stratified by their intra-tumoral PRC1 expression levels (Low: IRS < 2; Moderate: IRS 2–5; High: IRS > 5). Two-sided Mantel-Haenszel test.