Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 16;11:18513. doi: 10.1038/s41598-021-97728-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Detection of macrophages in the lung tissue and BALF. Representative microphotographs of sequential sections of lung tissue of saline (a and d), BLM, (b and e) and BLM + NINT treated mice (c and f) at day 28. (a, b, c: H&E staining; d, e, f: immunofluorescent staining for CD206 and DAPI). Residual macrophage cells in lung tissue after bronchoalveolar lavage are indicated with black arrowheads in the H&E images. White arrowheads indicate macrophages expressing CD206⁺ in IF images. (g) Absolute number of CD206⁺ macrophages counted by FACS in saline, BLM and BLM + NINT-treated mice. Data are shown as mean values ± S.E.M. for 8 mice per group. Asterisks indicate significant statistical differences in comparison with BLM group (***P < 0.001; ANOVA followed by Dunnett’s test). The percentage on the BLM + NINT bars represents the inhibition effect of the treatment compared to BLM.