. 2021 Sep 16;11:18455. doi: 10.1038/s41598-021-97686-6

Table 2.

Biochemical and oxidative stress status markers of examined population according to NAFLD status.

	Non-NAFLD N = 56	NAFLD N = 122	p
Glucose, mmol/L	5.5 (5.2–5.8)	6.4 (5.5–8.3)	< 0.001
HbA1c, %	5.3 (5.1–5.6)	6.0 (5.5–7.0)	< 0.001
TC, mmol/L	5.93 (4.86–6.66)	5.92 (4.93–6.88)	0.612
HDL-c, mmol/L^#	1.78 ± 0.41	1.21 ± 0.30	< 0.001
LDL-c, mmol/L	3.50 (2.71–4.07)	3.43 (2.76–4.34)	0.383
TG, mmol/L	1.15 (0.94–1.39)	2.28 (1.73–2.95)	< 0.001
CRI-I	3.30 (2.77–3.68)	4.98 (4.15–5.96)	< 0.001
CRI-II	1.98 (1.50–2.33)	2.93 (2.41–3.79)	< 0.001
hsCRP, mg/L	0.52 (0.32–1.07)	1.73 (0.79–3.11)	< 0.001
AST, U/L	20 (17–22)	19 (17–24)	0.838
ALT, U/L	15 (11–20)	23 (17–31)	< 0.001
GGT, U/L	11 (9–15)	23 (16–31)	< 0.001
AOPP, μmol/L	32.10 (30.60–38.65)	49.35 (40.00–62.00)	< 0.001
PAB, HKU	119 (97.97–142)	102 (66.87–129)	0.068
TOS, μmol/L H₂O₂ equivalent/L	6.30 (4.10–18.33)	12.70 (7.50–19.20)	0.003
TAS, μmol/L Trolox equivalent/L	1170 (1075–1269)	1212 (1136–1318)	0.042
OSI, arbitrary unit	0.51 (0.35–1.54)	1.06 (0.58–1.65)	0.008

Data are presented as median (interquartile range) and compared with Mann–Whitney U-test.

^# Normally distributed data are presented as arithmetic mean ± standard deviation and compared with Student t-test.

Categorical variables are presented as relative frequencies and compared by Chi-square test for contingency tables.

HbA1c-Glycated hemoglobin; TC-Total cholesterol; HDL-c-High density lipoprotein cholesterol; LDL-c-Low density lipoprotein cholesterol; TG-Triglycerides; CRI-I-Castelli’s Risk Index I; CRI-II-Castelli’s Risk Index II; hsCRP-High sensitivity C–reactive protein; AST-Aspartate aminotransferase; ALT-Alanine aminotransferase; GGT-Gamma glutamyl transferase; AOPP-Advanced oxidation protein products; PAB-Prooxidant-antioxidant balance; TOS-Total oxidant status; TAS-Total antioxidant status; OSI-Oxidative-stress index.