Table 1.
Clinical data of included patients in total population and according to wound evolution (improved vs stagnated/worsened).
| Variable | Total population (n = 24) | Improved (n = 15) | Stagnated/worsened (n = 9) | P-value | |
|---|---|---|---|---|---|
| Sex | Female | 9 (37.5%) | 8 (53.3%) | 1 (11.1%) | 0.0803 |
| Age | Years | 61.5 (55.5, 67) | 64 (57.5, 67.5) | 54 (49, 66) | 0.148 |
| Body mass index (kg/m2) | < 18.5 | 2 (8.3%) | 1 (6.7%) | 1 (11.1%) | 0.933 |
| 18.5–25 < | 7 (29.2%) | 4 (26.7%) | 3 (33.3%) | ||
| 25–30 < | 10 (41.7%) | 7 (46.7%) | 3 (33.3%) | ||
| ≥ 30 | 5 (20.8%) | 3 (20%) | 2 (22.2%) | ||
| Weight change (%) | % reductiona | 0 (− 1.3, 1.1) | 0 (− 1.01, 1.70) | 0 (− 1.2, 0) | 0.346 |
| Undernutrition | None | 9 (37.5%) | 5 (33.3%) | 4 (44.4%) | 0.649 |
| Scoreb | |||||
| Moderate | 6 (25%) | 5 (33.3%) | 1 (11.1%) | ||
| Severe | 9 (37.5%) | 5 (33.3%) | 4 (44.4%) | ||
| CRP (D0) | mg/l | 16.5 (8.5, 40.75) | 22 (9, 46.5) | 13 (9,22) | 0.633 |
| CRP (D28) | 14 (5.5, 23.5) | 20 (5.5, 23.5) | 11 (6.25, 23) | 0.747 | |
| Wound stage (D0) | III | 16 (66.7%) | 9 (60%) | 7 (77.8%) | 0.657 |
| IV | 8 (33.3%) | 6 (40%) | 2 (22.2%) | ||
| Wound stage (D28) | II | 2 (8.3%) | 2 (13.3%) | 0 (0%) | 0.678 |
| III | 15 (62.5%) | 9 (60%) | 6 (66.7%) | ||
| IV | 7 (29.2%) | 4 (26.7%) | 3 (33.3%) | ||
| Wound localisation | Ischial | 12 (50%) | 7 (46.7%) | 5 (55.6%) | |
| Sacral | 11 (45.8%) | 8 (53.3%) | 3 (33.3%) | 0.384 | |
| Trochanteric | 1 (4.2%) | 0 (0%) | 1 (11.1%) | ||
| Area of woundc | % reductiona | − 22.19 (− 45.9, 15.98) | − 40.2 (− 55.46, 23.22) | 5.88 (− 19.37, 15) | 0.138 |
| Depth of wound | % reductiona | − 17.78 (− 55, 40) | − 40.59 (− 57.5, − 4.44) | 33.33 (− 2.22, 50) | 0,185 |
| Duration of wound | Months | 6.26 (2.52, 16.21) | 6.28 (3.42, 14.89) | 6.02 (1.77 14.63) | 0.698 |
| Detachment (D0) | Yes (n; %) | 13 (54.2%) | 10 (66.7%) | 3 (33.3%) | 0.206 |
| Detachment (D28) | Yes (n; %) | 13 (54.2%) | 9 (60%) | 4 (44.4%) | 0.675 |
| Amount of exudate (D0) | None | 0 (0%) | 0 (0%) | 0 (0%) | 0.334 |
| + | 9 (37.5%) | 4 (26.7%) | 5 (55.6%) | ||
| ++ | 9 (37.5%) | 6 (40%) | 3 (33.3%) | ||
| +++ | 6 (25%) | 5 (33.3%) | 1 (11.1%) | ||
| Initial treatment | Yes (n; %) | 12 (50%) | 9 (60%) | 3 (33.3%) | 0.4 |
| Antibiotherapy | Yes (n; %) | 5 (20.8%) | 4 (26.7%) | 1 (11.1%) | 0.615 |
Quantitative variables are expressed as median (Q1, Q3) and qualitative variables as absolute frequency (relative frequency in %). The statistical tests are either Student or Wilcoxon for quantitative variables and Chi-squared or Fisher’s exact for qualitative variables.
a100 × (D28-D0)/D0, bin accordance to28, cKundin’s formula29.