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. 2021 Sep 16;12(10):852. doi: 10.1038/s41419-021-04143-3

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A Schematic diagram of AMI model and the stages for transcriptome and proteome profiling. Eighteen mice were randomly divided into six groups. AMI was established by ligation of the proximal left anterior descending coronary artery indicated by the circled “x”. B Schematic diagram shows the infarct region indicated by dotted area. C Principal component analysis (PCA) of the transcriptome (left) and the proteome (right). Arrowed lines indicate the trajectory of AMI progress. D The correlation between the transcriptome and proteome profiles.