Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 16;12(10):852. doi: 10.1038/s41419-021-04143-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 2 — A The number of the differentially expressed genes (DEGs) between AMI samples and the control sample. Red: upregulated, blue: downregulated. B Bubble diagram shows the significantly enriched GO terms (biological processes) of upregulated DEGs. C Masson staining results show the morphologic changes in AMI samples compared to the control sample. The arrows indicate the damaged cardiomyocytes at 1, 6 and 24 h. At 1 h, the cytoplasm of the cardiomyocytes begins to swell, and then the cells begin to disintegrate at 6 h; the fibrosis were found around the cardiomyocytes at 24 h, and the space made by the dead cardiomyocytes was occupied by red blood cells and immune cells at 72 h (Bar = 50 μm). D The composition of immune cells in the infarcted myocardia at different stages of AMI. CM cardiac myocytes, CF cardiac fibroblasts. E The dynamic proportion of the representative types of immune cells in the course of AMI development, indicating the activation of immune infiltration.