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. 2021 Sep 16;11:18451. doi: 10.1038/s41598-021-97908-x

Table 3.

Histopathological ischemic brain changes in rats.

Group Dose n Histopathological grading of ischemic brain in rats
+ ++ +++ ++++ P value
Sham operation group 6 6 0 0 0 0 0.002**
Model group 6 0 0 4 2 0 1.000
Nimodipine injection group 0.5 mg/kg 6 3 2 0 1 0 0.031*
E. breviscapus injection group 5 mL/kg/d 6 1 4 0 1 0 0.030*
Scutellarin group 1.1505 mg/kg 6 2 1 3 0 0 0.031*
3,5-Dicaffeoylquinic acid group 0.2335 mg/kg 6 3 1 2 0 0 0.016*

*Compared with the model group, *P < 0.05 and **P < 0.01.