Table 5.

Effects of drugs on the expression of iNOS, MMP-9, claudin-5, occludin and ZO-1mRNA levels in the ischemic brain tissue of MCAO rats.

Group	Dose	n	iNOS		MMP-9		Claudin-5		Occludin		ZO-1
			$\overline{x}\pm s$	P value	$\overline{x}\pm s$	P value	$\overline{x}\pm s$	P value	$\overline{x}\pm s$	P value	$\overline{x}\pm s$	P value
Sham operation group	–	6	2.96 ± 2.53	0.140	3.05 ± 2.92	0.074	0.88 ± 0.31	0.107	3.59 ± 2.91	0.513	1.07 ± 0.61	0.007**
Model group	–	6	8.62 ± 4.92	–	10.59 ± 9.01	–	0.45 ± 0.14	–	2.98 ± 1.37	–	0.51 ± 0.21	–
Nimodipine injection group	0.5 mg/kg	6	9.12 ± 9.26	0.894	7.77 ± 9.40	0.494	0.57 ± 0.20	0.656	2.39 ± 2.04	0.528	0.43 ± 0.31	0.683
E. breviscapus injection group	5 mL/kg/day	6	4.88 ± 2.52	0.325	10.35 ± 7.46	0.953	0.57 ± 0.19	0.638	3.77 ± 1.22	0.396	0.53 ± 0.32	0.905
Scutellarin group	1.1505 mg/kg	6	7.84 ± 9.93	0.836	3.06 ± 5.09	0.074	0.43 ± 0.21	0.933	1.82 ± 1.06	0.217	0.41 ± 0.18	0.621
3,5-Dicaffeoylquinic acid group	0.2335 mg/kg	6	7.60 ± 5.45	0.787	6.53 ± 6.22	0.326	1.07 ± 0.97	0.022*	3.84 ± 1.34	0.354	0.55 ± 0.15	0.825