Table 6.

Effects of drugs on the expression of iNOS, MMP-9, claudin-5, occludin and ZO-1protein levels in the ischemic brain tissue of MCAO rats.

Group	Dose	n	iNOS		MMP-9		Claudin-5		Occludin		ZO-1
			$\overline{x}\pm s$	P value	$\overline{x}\pm s$	P value	$\overline{x}\pm s$	P value	$\overline{x}\pm s$	P value	$\overline{x}\pm s$	P value
Sham operation group	–	6	1.00 ± 0.00	0.000**	1.00 ± 0.00	0.000**	1.00 ± 0.00	0.000**	1.00 ± 0.00	0.357	1.00 ± 0.00	0.013*
Model group	–	6	2.45 ± 0.84	–	1.85 ± 0.21	–	0.48 ± 0.20	–	0.92 ± 0.21	–	0.69 ± 0.29	–
Nimodipine injection group	0.5 mg/kg	6	1.96 ± 0.56	0.092	1.45 ± 0.14	0.013*	0.70 ± 0.28	0.056	0.97 ± 0.09	0.533	0.76 ± 0.20	0.565
E. breviscapus injection group	5 mL/kg/d	6	1.61 ± 0.34	0.006**	1.40 ± 0.23	0.005**	0.61 ± 0.17	0.234	0.91 ± 0.10	0.880	0.76 ± 0.15	0.556
Scutellarin group	1.1505 mg/kg	6	1.51 ± 0.34	0.002**	1.27 ± 0.21	0.000**	0.56 ± 0.23	0.463	0.88 ± 0.24	0.636	0.83 ± 0.25	0.254
3,5-Dicaffeoylquinic acid group	0.2335 mg/kg	6	1.58 ± 0.40	0.004**	1.37 ± 0.48	0.003**	0.82 ± 0.12	0.004**	0.87 ± 0.13	0.610	0.93 ± 0.21	0.052