Skip to main content
. 2021 Sep 3;12:671201. doi: 10.3389/fimmu.2021.671201

Figure 4.

Figure 4

Estimation of infiltrating immune cells in the endometria of fertile and infertile cohorts (GSE120103) by the MCP-counter method. (A) The heatmap shows the absolute abundance of eight immune cell subsets. (B) Boxplots show differential infiltrating immune cells (CD8 T cells and cytotoxic lymphocytes) between fertile (n = 18) and infertile (n = 18) groups. (C) The ROC curve of CD8+ T cells in fertile and infertile cohorts (n = 36). (D) Boxplots show differential infiltrating immune cells (CD8 T cells, cytotoxic lymphocytes, and B lineage) between fertile (n = 9) and infertile (n = 9) groups in patients with endometriosis. (E) The ROC curve of CD8+ T cells in patients with endometriosis (n = 18). (F) Boxplots showing differentially infiltrating immune cells (NK cells and B lineage) in women with (n = 18) or without (n = 18) endometriosis. (G) The ROC curve of NK cells in women with or without endometriosis (n = 36). (H) Boxplots show differential immune cells (cytotoxic lymphocytes, B lineage, NK cells, and myeloid dendritic cells) between fertile (n = 9) and infertile (n = 9) groups in healthy women. (I) The ROC curve of NK cells in a cohort of healthy women (n = 18). Data were assessed by the Wilcoxon rank-sum test. *P < 0.05, **P < 0.01, and ***P < 0.001. AUC, the area under the ROC curve.