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. 2021 Sep 3;15:719388. doi: 10.3389/fnhum.2021.719388

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Copyright © 2021 Lindén and Berg.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Neuronal imaging of calcium-dependent fluorescent signal in zebrafish larvae hindbrain during visuomotor response has a skewed lognormal-like distribution in peak signal. (A) In-vivo tail-bending in response to visual input. (B) Fluorescent signal (ΔF/F) at neuronal resolution of a glycinergic subpopulation which provide inhibitory feedback during escape response (50 cells shown). (C) The maximal calcium response across cells in the population is skewed and lognormal-like (lognormal fit, gray line). (D) Same distribution on log scale resembles a normal distribution (gray fit). (E) High skewness across the cohort (n = 10 animals). (F) Skewness on a log scale is closer to zero, i.e., normal distribution. Data kindly provided by Severi et al. (2018) and reanalyzed with permission.