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. 2021 Sep 3;12:668974. doi: 10.3389/fimmu.2021.668974

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Copyright © 2021 Chen, Tu, Zou, Zhu, Zhao and Qin

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlation analysis of MPO-DNA, NE, and DNase with cf-DNA in isolated NETs. Correlation analysis showing that MPO-DNA (A) and NE (B) were highly correlated with circulating cf-DNA levels (MPO-DNA, r² = 0.766, P < 0.001, NE, r² = 0.687, P < 0.001). The opposite was found between cf-DNA and DNase levels (C) (r² = 0.433, P < 0.001).