FIGURE 3.

AURKA is involved in the cell cycle and tp53 signal pathway. (A) The co‐expression network is shown for all genes that have significant correlation with AURKA. (B) The enrichment results shown for all genes in co‐expression network. ClueGo application in Cytoscape was used for enrichment based on Reactome database. (C) CCNB1 expression is shown in CRC and GC samples compared to normal adjacent samples. Also, the co‐expression between AURKA and CCNB1 levels in CRC and GC samples is indicated. (D) The enrichment results of genes affected by changes in AURKA expression are shown in GSE57931. (E) The frequency and different types of AURKA gene mutations are shown for all 13 common cancers based on TCGA data