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. 2021 Sep 3;12:692496. doi: 10.3389/fphys.2021.692496

FIGURE 4.

FIGURE 4

Signal-to-noise ratio versus detection area. Representative optical recording of optogenetically induced APs collected from different-sized surface areas (2 Hz stimulation frequency with blue light pulses duration of 30 ms). Reduction of the detection area from the whole well area (≈190 mm2) to 0.17 mm2, reduced the signal-to-noise ratio from ≈ 600 to ≈ 2. The estimated number of cells present in the different-sized detected area is indicated in the right column.