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. 2021 Sep 3;12:715693. doi: 10.3389/fphys.2021.715693

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Copyright © 2021 Prem and Kurian.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Mitochondrial electron transport chain (ETC) enzymes in ND and HD renal tissue subjected to IR injury. (A) Complex I activity, (B) Complex II activity, (C) Complex III activity, and (D) Complex IV activity. Complex I activity was expressed as μmol NADH oxidized/min/mg protein; Complex II activity was expressed in μmol DCPIP reduced/min/mg protein; Complex III activity was expressed in μmol Cytochrome C reduced/min/mg protein; Complex IV activity was expressed in μmol Cytochrome C oxidized/min/mg protein. *p < 0.05 vs. D, ^#p < 0.05 vs. ND-IR. The data are presented as mean ± SD (n =6/group). ND, Normal diet fed; FD, High fat diet fed; IR, Ischemia-reperfusion.