Table 2.
Univariate survival analysis of clinical parameters and the risk score with PFS and OS in the Tianjin cohort.
| Clinical parameters | n | PFS | p-value | OS | p-value | |
|---|---|---|---|---|---|---|
| Hazard ratio | Hazard ratio | |||||
| (95% CI) | (95% CI) | |||||
| Age (years) | ||||||
| <65 | 132 | 1.299 | 0.227 | 1.336 | 0.282 | |
| ≥65 | 48 | (0.825~2.046) | (0.760~2.348) | |||
| Gender | ||||||
| Males | 79 | 0.846 | 0.403 | 0.732 | 0.212 | |
| Females | 101 | (0.568~1.261) | (0.443~1.208) | |||
| Clinical stage | ||||||
| I+II | 122 | 3.304 | <0.0001*** | 4.834 | <0.0001*** | |
| III | 58 | (2.067~5.281) | (2.710~8.623) | |||
| Tumor | ||||||
| T1 | 95 | 2.300 | <0.0001*** | 2.408 | 0.0005*** | |
| T2+T3+T4 | 85 | (1.536~3.444) | (1.460~3.971) | |||
| Lymph node | ||||||
| N0 | 113 | 2.954 | <0.0001*** | 4.387 | <0.0001*** | |
| N1+N2 | 67 | (1.913~4.562) | (2.557~7.527) | |||
| Smoke | ||||||
| No smoking | 114 | 1.091 | 0.675 | 1.364 | 0.221 | |
| Smoking | 66 | (0.721~1.652) | (0.810~2.298) | |||
| PTTG1 | ||||||
| Low | 75 | 3.936 | <0.0001*** | 3.798 | <0.0001*** | |
| High | 105 | (2.654~5.837) | (2.316~6.228) | |||
| SLC2A1 | ||||||
| Low | 81 | 4.105 | <0.0001*** | 8.024 | <0.0001*** | |
| High | 99 | (2.758~6.110) | (4.890~13.17) | |||
| FAM83A | ||||||
| Low | 128 | 2.943 | <0.0001*** | 3.909 | <0.0001*** | |
| High | 52 | (1.809~4.785) | (2.175~7.025) | |||
| Risk score | ||||||
| Low | 93 | 5.519 | <0.0001*** | 10.96 | <0.0001*** | |
| High | 87 | (3.638~8.372) | (6.597~18.20) | |||
***p < 0.001.
Bold values indicate statistical significance p < 0.05.