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. 2021 Sep 3;12:723172. doi: 10.3389/fimmu.2021.723172

Table 2.

Univariate survival analysis of clinical parameters and the risk score with PFS and OS in the Tianjin cohort.

Clinical parameters n PFS p-value OS p-value
Hazard ratio Hazard ratio
(95% CI) (95% CI)
Age (years)
<65 132 1.299 0.227 1.336 0.282
≥65 48 (0.825~2.046) (0.760~2.348)
Gender
Males 79 0.846 0.403 0.732 0.212
Females 101 (0.568~1.261) (0.443~1.208)
Clinical stage
I+II 122 3.304 <0.0001*** 4.834 <0.0001***
III 58 (2.067~5.281) (2.710~8.623)
Tumor
T1 95 2.300 <0.0001*** 2.408 0.0005***
T2+T3+T4 85 (1.536~3.444) (1.460~3.971)
Lymph node
N0 113 2.954 <0.0001*** 4.387 <0.0001***
N1+N2 67 (1.913~4.562) (2.557~7.527)
Smoke
No smoking 114 1.091 0.675 1.364 0.221
Smoking 66 (0.721~1.652) (0.810~2.298)
PTTG1
Low 75 3.936 <0.0001*** 3.798 <0.0001***
High 105 (2.654~5.837) (2.316~6.228)
SLC2A1
Low 81 4.105 <0.0001*** 8.024 <0.0001***
High 99 (2.758~6.110) (4.890~13.17)
FAM83A
Low 128 2.943 <0.0001*** 3.909 <0.0001***
High 52 (1.809~4.785) (2.175~7.025)
Risk score
Low 93 5.519 <0.0001*** 10.96 <0.0001***
High 87 (3.638~8.372) (6.597~18.20)

***p < 0.001.

Bold values indicate statistical significance p < 0.05.