FIGURE 6.

Modulation of β-1, 4-GalT V on inflammatory factors in vivo. SD rats wereinjected intracortical with designated lentivirus particles as indicated following intraperitoneal injection of LPS (0.5 mg/kg, 6 h) for the inflammation model. Quantification of β-1,4-GalT V (A), IL-1β (B), TNF-α (D), Arg1 (F) expression in the cerebral cortex tissue by RT-PCR. (C,E) Quantification of IL-1β and TNF-α expression, respectively by ELSA. (G) Representative blots of Arg1. (H) Quantification of Arg1 in panel (G). Groups significantly different from non-treated sham group, LPS-treated sham group were marked by asterisks, hashtags respectively. Data are expressed as mean ± SD; n = 3; *p < 0.05, **p < 0.01, ***p < 0.001, ^#p < 0.05, ^##p < 0.01, ^###p < 0.001.