Table 1.
Outcome | Number of (sub)studies | Effect size* | p-value | I2 | p-value |
---|---|---|---|---|---|
In-hospital mortality | 49 | 7.22 (5.27–9.88) | <0.001 | 62% | <0.001 |
Need for RRT | 50 | 18.84 (11.65–30.47) | <0.001 | 71% | <0.001 |
Cardiac arrhythmias | 10 | 2.67 (1.86–4.80) | <0.001 | 40% | 0.091 |
Ventilation time (days) | 34 | 1.76 (1.05–2.47) | <0.001 | 99% | <0.001 |
PICU length of stay (days) | 38 | 3.31 (2.52–4.10) | <0.001 | 97% | <0.001 |
Hospital length of stay (days) | 36 | 5.00 (3.34–6.67) | <0.001 | 98% | <0.001 |
AKI, acute kidney injury; PICU, pediatric intensive care unit; RRT, renal replacement therapy.
Effect sizes are presented as odds ratios for binary outcomes and mean differences for continuous outcomes. Significant p-values (p < 0.05) are indicated in bold.