Table 3.
Scientific evidence for the potential application of allopathic anti-cancerous drugs using nanofibers
| Excipient | Drug(s) | Application | Ref. |
| PLA | 5-FU/OX | In-vitro and In-vivo on colorectal cancer cells | [22] |
| PCL | 5-FU/PTX | In-vitro on prostatic and breast cancer cells | [55] |
| PCL/CS | 5-FU | In-vitro on colorectal cancer cells | [15] |
| PBAT | 5-FU/CUR | In-vitro on colorectal cancer cells | [56] |
| P(NIPAAM-AAm-VP) | DOX | In-vitro on A-549 lung cancer cells | [57] |
| PLGA | DOX/CPT | In-vitro and In-vivo on HeLa cervical cancer cells | [58] |
| PLGA/GEL | DOX/CPT | In-vitro on HepG-2 liver cancer cells | [59] |
| PEG-PCL | DOX/CUR | In-vitro on HeLa cervical cancer cells | [50] |
| PEO/CS | DOX | In-vitro on lung cancer cells | [60] |
| PLLA | DOX | In-vitro and In-vivo on breast cancer cells | [61] |
| PLGA/GEL | DOX | In-vitro on Caco-2, 4T1 and 431 cancer cells | [62] |
| PCL | DOX | In-vitro on carcinoma cells, cervical cancer cells, and breast cancer cells | [63] |
| PLGA | PTX | In-vitro on C6 Glioma cancer cells | [64] |
| PEO/CS | PTX | In-vitro on prostate cancer cells | [16] |
| PU | PTX | In-vitro and In-vivo on CT-26 colon cancer cells | [65] |
| PLLA | PTX | In-vitro on HepG-2 cancer cells | [66] |
| PCL | PTX | In-vitro on liver cancer cells | [67] |
| PLGA | PTX/BFA | In-vitro on HepG-2 cancer cells | [68] |
| SA | PTX | In-vitro and In-vivo on A549 lung cancer cells | [69] |
| SnO2 | PTX | In-vitro on liver cancer cells | [70] |
| CA | PTX | In-vitro on Gastric adenocarcinoma SGC7901 cancer cells | [71] |
| PLA | PTX | In-vitro and In-vivo on Glioblastoma brain tumor cells | [72] |
| PLGA/CS | PTX | In-vitro and In-vivo on prostate cancer cells | [73] |
| PLA/PEG | PTX | In-vitro and In-vivo on Fibrosarcoma HT1080 cancer cells | [74] |
| PCPP-CA-PHM | PTX | In-vitro on breast cancer cells | [75] |
| PLLA | CIS | In-vitro on lung spc-a-1 cancer cells | [76] |
| PLGA | BCNU, Irinotecan, and CIS | In-vitro and In-vivo on Glioblastoma multiforme brain cancer cells | [77] |
| PCL/CS | CIS | In-vitro on MCF-7 breast cancer cells | [78] |
| PCL/PU | TMZ | In-vitro on U-87 MG glioblastoma cancer cells | [79] |
| PCL/PU | TMZ | In-vitro on Glioblastoma cancer cells | [80] |
| PVA | DTX | In-vitro on breast cancer cells | [81] |
| PLA | DTX | In-vitro and In-vivo on breast cancer cells | [82] |
| PEG-PLLA | BCNU | In-vitro on Glioma C6 cancer cells | [83] |
| Cellulose | Metformin | In-vitro on Melanoma cancer cells | [84] |
| PLA - HA | GEM | In-vitro on pancreatic cancer cells | [85] |