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Association between glycolysis transporter, key enzymes, and PI3K, HIF-1, C-MYC signaling pathways. PI3K, HIF-1, and C-MYC signaling pathways can activate the expression of key glycolysis enzymes and transporters to ensure cancer metabolism and energy supply; at the same time, the key enzymes and transporters of glycolysis can activate chemoresistance-related signaling pathways through their own or other protein mediators.
