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. 2021 Sep 3;8:730316. doi: 10.3389/fcvm.2021.730316

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Copyright © 2021 Morales, van den Boomen, Nguyen, Kalpathy-Cramer, Rosen, Stultz, Izquierdo-Garcia and Catana.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Overview of proposed DeepStrain workflow. VCN centers and crops the input pair of cine-MRI frames. Tissue labels generated by CarSON are used to build an anatomical model. Motion estimates derived from CarMEN are used to calculate strain measures, and these estimates are combined with the anatomical model to enable global and regional strain analyses.