Table 2.

The effect of genetic variation of ACE and AGTR1 genes on breast cancer in different ethnicity (53, 55).

Country/Population	Gene Polymorphism	Breast cancer association
Mexican women	D allele of ACE gene	Increase risk of breast cancer
Mexican and Caucasian women	C allele of AGTR1 gene	Decrease risk of breast cancer
Chinese women	AA (A240T) and insertion homozygote (II) of ACE gene	Decrease risk of breast cancer
Egyptian postmenopausal women	C allele of AGTR1 gene	Increase risk of breast cancer
Kashmiri women	Insertion homozygote (II) of ACE gene	Increase risk of breast cancer
	ACE heterozygote (ID) genotype	Decrease risk of breast cancer
Ukrainian women	AC genotype of AGTR1 and D allele of ACE gene	Increase risk of breast cancer
North Indian women	AC, CC (A1166C) and C allele of AGTR1 Deletion homozygote (DD) and D allele of ACE gene	Increase risk of breast cancer
	Insertion homozygote (II) of ACE gene	Decrease risk of breast cancer