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. 2021 Sep 3;11:688882. doi: 10.3389/fonc.2021.688882

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Copyright © 2021 Zhao, Zhou, Shen, Yang, Deng, Li and Cui

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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DCLK3 mediated biological functions of miR-1236-3p in colon cancer cells. SW620 cells were co-transfected with miR-1236-3p mimic, mimic control, inhibitor, inhibitor control, overexpression (pcDNA3.1-DCLK3) and knockdown (si-DCLK3) of DCLK3. DCLK3 expressions were determined by western blotting (A) and qRT-PCR (B). The CCK-8 at 450 nm (C), transwell migration (D), and invasion (E) assays were performed in SW620 cells. Error bars represent the mean ± s.e.m. *P < 0.05, **P < 0.01, ***P < 0.001 by Student’s t-test, six replicates per group.