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. 2021 Sep 3;11:688882. doi: 10.3389/fonc.2021.688882

Table 3.

Differently expressed miRNA expressions in colon cancer and normal colon tissues in discovery, training and validation sets.

miRNAs Discovery set (n = 10) Training set (n = 70) Validation set (n = 70)
logFC adj. P value FC P value FC P value
Up-regulated
 hsa-miR-4800-3p 1.01 0.00016* 2.21 0.013* 1.6 0.22
 hsa-miR-4449 1.98 0.00035* 2.52 0.008* 2.1 0.15
 hsa-miR-652 1.22 0.00040* 2.01 0.42
 hsa-miR-3679-5p 1.03 0.00052* 2.33 0.009* 1.8 0.087
 hsa-miR-182 1.03 0.00188* 1.63 0.16
 hsa-miR-181d 1.01 0.00201* 1.81 0.38
 hsa-miR-4322 1.06 0.00236* 1.42 0.73
 hsa-miR-708 1.15 0.00295* 1.33 0.33
 hsa-miR-4498 1.07 0.00452* 2.14 0.35
 hsa-miR-324-5p 1.06 0.00583* 1.55 0.18
 hsa-miR-92a 1.40 0.00664* 1.36 0. 22
 hsa-miR-3687 1.48 0.01109* 2.21 0.07
 hsa-miR-3162-5p 1.01 0.01309* 1.53 0.69
 hsa-miR-3651 1.25 0.01363* 1.43 0.43
 hsa-miR-3195 1.06 0.01500* 1.22 0.76
 hsa-miR-203 1.14 0.01565* 1.61 0.09
 hsa-miR-4634 1.12 0.01811* 1.42 0.61
 hsa-miR-3175 1.19 0.02238* 2.13 0.09
 hsa-miR-107 1.15 0.03508* 1.44 0.54
Down-regulated
 hsa-miR-4727-5p -1.15 0.00001* 0.65 0.25
 hsa-miR-1236-3p -1.02 0.00004* 0.31 0.004* 0.33 0.002*
 hsa-let-7f-2 -1.03 0.00008* 0.34 0.028* 0.55 0.08
 hsa-miR-4304 -1.00 0.00009* 0.28 0.011* 0.48 0.09
 hsa-miR-126 -1.12 0.00012* 0.67 0.33
 hsa-miR-539 -1.01 0.00016* 0.88 0.31
 hsa-miR-139-5p -1.32 0.00441* 0.85 0.45
 hsa-miR-320e -1.15 0.00597* 0.66 0.15
 hsa-miR-378 -1.12 0.01855* 0.59 0.11
 hsa-miR-451 -1.11 0.02517* 0.71 0.21
 hsa-miR-320a -1.18 0.04261* 0.63 0.09

FC, fold change; *P < 0.05.