Table 3.
Short-term outcomes of infants hospitalized until discharge home at the University hospital of Strasbourg, during each study period, with adjustment for gestational age.
| Outcome | 2007–2008 | 2010-2011 | 2013-2014 | P * | |
|---|---|---|---|---|---|
| (n = 34) | (n = 42) | (n = 66) | |||
| Duration of hospitalization (days), median (range) | 84 (24,154) | 94 (15,172) | 83 (15,148) | 0.97 | |
| Respiratory outcomes (days), median (range) | |||||
| Duration of mechanical ventilation | 19 (1,51) | 12.5 (1,49) | 11.5 (1,74) | 0.02 | |
| Age at extubation | 6 (1,43) | 6 (1,43) | 3 (1–41) | 0.02 | |
| Duration of CPAP | 29.5 (0,64) | 48 (0,75) | 53 (0–106) | 0.001 | |
| Duration of 02 | 53.5 (1,118) | 36 (1,172) | 27.5 (1–140) | 0.25 | |
| Neurological outcomes, n(%) | |||||
| ROP | 2 (5.9) | 6 (14.3) | 11 (16.7) | 0.14 | |
| PVLM | 2 (5.9) | 0 (0) | 8 (12.5) | 0.31 | |
| IVH | None | 29 (85.3) | 23 (54.8) | 45 (68.2) | 0.15 |
| Grade 1,2 | 3 (8.8) | 15 (35.7) | 17 (25.8) | 0.09 | |
| Grade 3,4 | 2 (5.9) | 4 (9.5) | 4 (6.1) | 0.75 | |
| NEC, n(%) | 5 (14.7) | 10 (23.8) | 13 (19.7) | 0.53 | |
| Infection, n(%) | |||||
| Bacterial LONI | None | 6 (17.6) | 7 (16.7) | 13 (19.7) | 0.22 |
| Probable | 8 (23.5) | 7 (16.7) | 15 (22.7) | 0.96 | |
| Certain | 20 (58.8) | 28 (66.7) | 38 (57.6) | 0.39 | |
| Fungal LONI | 5 (14.7) | 7 (16.7) | 16 (24.2) | 0.27 | |
| Age at full enteral feeding (days), median (range) | 45 (31,150) | 49 (23,130) | 46 (18,116) | 0.09 | |
| Weight at discharge (g), mean (SD) | 2276 (412) | 2634 (598) | 2635 (422) | 0.02 | |
*
Comparison of the first period (2007–2008) and third period (2013–2014).
LONI, late onset neonatal infection; NEC, necrotizing enterocolitis; ROP, retinopathy of prematurity; IVH, intraventricular hemorrhage; PVLM, periventricular leukomalacia.