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. 2021 Sep 3;12:707267. doi: 10.3389/fimmu.2021.707267

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Copyright © 2021 Altaie, Venkatachalam, Samaranayake, Soliman and Hamoudi

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Top 20 pathways and functional enrichment analysis using Metascape. The y-axis shows significantly enriched gene ontology terms of the target genes. The darker the color, the higher the gene counts included in that pathway. The x-axis shows the enrichment scores of the gene ontology terms. P-value is calculated according to the count of the provided genes found in the given pathway. Log10(P) is the P-value in log base 10. P-value ≤0.05 was considered as significant. (A) Healthy control. (B) Periapical abscess. (C) Radicular cyst. (D) Periapical granuloma.