Table 10.

Molecular networks between Phb1^+/− and WT.

Network_ID	Molecules in network	Score	Focus molecules	Top diseases and functions
1	ACADL, ADIPOQ, CAT, CLOCK, COL1A1, CYP51A1, Cyp2c40 (includes others), DBI, FABP5, FDPS, IDI1, IGFBP4, LEPR, MAPK14, MBTPS1, MIF, MSMO1, NFIL3, NSDHL, Ncoa6, P4HB, PCSK9, PEMT, PER2, PLIN5, PPARA, RDH11, RGCC, SCD, SELENBP1, SQLE, SREBF1, SULT1E1, TNF, USP2	28	16	Lipid metabolism, small molecule biochemistry, vitamin and mineral metabolism
2	ABCB4, ACTA2, APOE, CYP7A1, FABP1, FOXM1, HGF, HIF1A, KLF11, LEP, MIF, MMP2, NR1H4, PDGFC, PLAT, S1PR2, STAT3, TGFB1, TIMP1, ethanol	5	4	Cellular movement, hematological system development and function, immune cell trafficking
3	RASSF1, TUBB2B	2	1	Cell cycle, cellular assembly and organization, cellular function and maintenance
4	IFI16, MTOR, TNK1	2	1	Cancer, endocrine system disorders, organismal injury and abnormalities
5	GSTA1, GSTA3, Gsta1, MAF	2	1	Drug metabolism, glutathione depletion in liver, endocrine system development and function