Table 3. Unadjusted and Adjusted HIV Incidence, Death, and Time to Incident HIV or Deatha.
| Participant exposure | HIV incidence (n = 2551)b | Death (n = 2474)c | Time to incident HIV or death (n = 2474) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Unadjusted HR (95% CI) | P value | Adjusted HR (95% CI) | P value | Unadjusted HR (95% CI) | P value | Adjusted HR (95% CI) | P value | Unadjusted HR (95% CI) | P value | Adjusted HR (95% CI) | P value | |
| Institutional vs family-based setting | 1.33 (0.41-4.35) | .64 | 1.49 (0.46-4.83) | .50 | 0.29 (0.09-0.99) | .047 | 0.26 (0.07-1.02) | .05 | 0.70 (0.28-1.75) | .44 | 0.73 (0.29-1.86) | .51 |
| Street vs family-based setting | 13.33 (5.42-32.79) | <.001 | 17.31 (5.85-51.25) | <.001 | 7.76 (3.34-18.04) | <.001 | 5.46 (2.30-12.94) | <.001 | 8.84 (4.46-17.53) | <.001 | 7.82 (3.48-17.55) | <.001 |
| Male vs female | NA | NA | 0.28 (0.11-0.69) | .006 | NA | NA | 1.81 (0.81-4.01) | .15 | NA | NA | 0.69 (0.37-1.30) | .25 |
| Baseline age ≥12 y vs <12 y | NA | NA | 1.83 (0.74-4.51) | .19 | NA | NA | 2.02 (0.83-4.89) | .12 | NA | NA | 2.03 (0.99-4.16) | .05 |
| Baseline HIV-positive vs HIV-negative status | NA | NA | NA | NA | NA | NA | 6.84 (1.88-24.88) | .004 | NA | NA | NA | NA |
Abbreviations: HR, hazard ratio; NA, not applicable.
a
All models (adjusted and unadjusted) for HIV incidence and time to incident HIV or death omitted participants who had HIV-positive status at enrollment. The adjusted models were adjusted for age and sex.
b
Estimated using competing risks analysis, in which death was a competing risk for HIV infection.
c
The adjusted model for death was adjusted for baseline HIV status, age, and sex.