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Diagnostic power of the best cut-off of the % of BM progenitor cells expressing Tp53 with intensity score 3+ in IHC versus TP53 mutation analysis by NGS in the whole study group
| Tp53 mutation analysis by NGS | ||||
|---|---|---|---|---|
|
| ||||
| Mutated | Unmutated | |||
| % of BM progenitor cells expressing Tp53 with intensity score 3+ (intense) | ≥2.3% | 7 | 5 | 12 |
| <2.3% | 3 | 14 | 17 | |
| 10 | 19 | N = 29 | ||
NGS, next generation sequencing; BM, bone marrow.
