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. 2021 Sep 16;7(11):1635–1642. doi: 10.1001/jamaoncol.2021.3771

Table 2. 68Ga-PSMA-11 Test Characteristics for the Composite 3 Blinded Reads and Overall Majority Rule Read.

Test characteristic Read 1 Read 2 Read 3 Majority read
True positive 30 33 29 30
False positive 13 16 15 10
True negative 189 186 187 192
False negative 45 42 46 45
Sensitivitya 0.40 (0.30-0.51) 0.44 (0.33-0.55) 0.39 (0.28-0.50) 0.40 (0.30-0.51)
Specificitya 0.94 (0.89-0.96) 0.92 (0.88-0.95) 0.93 (0.88-0.95) 0.95 (0.91-0.97)
PPVa 0.70 (0.55-0.81) 0.67 (0.53-0.79) 0.66 (0.51-0.78) 0.75 (0.60-0.86)
NPVa 0.81 (0.75-0.85) 0.82 (0.76-0.86) 0.80 (0.75-0.85) 0.81 (0.76-0.85)

Abbreviations: NPV, negative predictive value; PPV, positive predictive value; PSMA, prostate-specific membrane antigen.

a

95% CIs in parentheses.