Table 2.
Blood gas analysis and ventilatory settings data of patients with extremely critical COVID‐19 who received ECMO and those who received conventional ventilation non‐ECMO
| ECMO (n = 34) | non‐ECMO (n = 31) | p value | ||
|---|---|---|---|---|
| PaO2/FiO2 (mmHg) | 69.6 (30.1) | 75.4 (43.8) | 0.535 | |
| PEEP (cmH2O) | 11 (2.1) | 9.3 (3.4) | 0.042 | |
| Plateau pressure (cmH2O)a | 29.9 (9.1) | 33.8 (8.5) | 0.146 | |
| Arterial blood pH | 7.29 (0.12) | 7.31 (0.16) | 0.546 | |
| PaCO2 (mmHg) | 61.6 (17.0) | 52.8 (20.1) | 0.065 | |
| Mode of ventilation no. (%) | ||||
| PRVC | 3 (8.8%) | 0 (0%) | 0.240 | |
| PCV | 15 (44.1%) | 17 (54.8%) | 0.388 | |
| VCV | 8 (23.5%) | 12 (38.7%) | 0.185 | |
| APRV | 1 (2.9%) | 0 (0%) | 1.000 | |
| AC | 4 (11.8%) | 0 (0%) | 0.115 | |
| Use of CRRT‐ no. (%) | 22 (64.7%) | 12 (38.7%) | 0.036 | |
| Use of prone ventilation‐ no. (%) | 25 (73.5%) | 5 (16.1%) | 0.000 | |
Note: Data are presented as numbers (%).
Abbreviations: AC, assisted‐control ventilation; APRV, airway pressure release ventilation; COVID‐19, coronavirus disease 2019; CRRT, continuous renal replacement therapy; ECMO, extracorporeal membrane oxygenation; PaO2/FiO2, arterial oxygen tension to inspired oxygen fraction ratio; PEEP, positive end‐expiratory pressure; PaCO2, partial pressure of arterial carbon dioxide; PCV, pressure‐controlled ventilation; PRVC, pressure‐regulatory volume control ventilation; VCV, volume‐controlled ventilation.
Data on plateau pressure was missing for six patients in the ECMO group and 11 in the control group.