TABLE A5.
Novavax supply chain
| Company/institution | Location | Role | Key dates |
|---|---|---|---|
| Novavax | Maryland, US | Identifies COVID‐19 vaccine candidate | 8 April 2020 |
| Drug substance | |||
| Emergent BioSolutions | Maryland, US | Manufactures drug substance for clinical trials | 8 April 2020 |
| Novavax | Bohumil, Czech Republic | Purchases plant expected to manufacture 1 billion doses of drug substance | 27 May 2020 |
| Fujifilm Diosynth Biotechnologies (FDB) | North Carolina, US | Manufactures drug substance | 23 July 2020 |
| FDB | Texas, US | Manufactures drug substance | 27 July 2020 |
| FDB | Billingham, UK | Manufactures drug substance | 14 August 2020 |
| Takeda Pharmaceutical | Hikari, Japan |
Signs collaboration agreement Reaches final agreement for drug substance manufacturing |
|
| SK bioscience | Andong L‐house, South Korea |
Signs collaboration agreement Reaches final agreement for drug substance manufacturing |
13 August 2020 |
| Biofabri | Spain | Manufactures drug substance | 21 October 2020 |
| Serum Institute of India (SII) | Pune, India |
Signs supply and license agreement Signs amendment for drug substance manufacturing |
30 July 2020 |
| National Research Council's Biologics Manufacturing Centre | Montréal, Canada | Signs Memorandum of Understanding with government of Canada for drug substance manufacturing | 2 February 2021 |
| Adjuvant | |||
| Desert King | California, US | Procures saponin (raw material) for adjuvant from its facilities in Chile | 30 September 2020 a |
| AGC Biologics | Copenhagen, Denmark | Manufactures Matrix‐M adjuvant | 4 June 2020 |
| AGC Biologics | Washington, US | Manufactures Matrix‐M adjuvant | 10 August 2020 |
| PolyPeptide Group | California, US | Manufactures Matrix‐M adjuvant | 3 June 2020 |
| PolyPeptide Group | Malmö, Sweden | Manufactures Matrix‐M adjuvant | 3 June 2020 |
| Fill and finish | |||
| Par Sterile Products (Endo) | Michigan, US | Handles fill and finish | 25 September 2020 |
| Baxter | Halle, Germany | Handles fill and finish | 11 January 2021 |
| GSK | Barnard Castle, England, UK | Handles fill and finish | 29 March 2021 |
| Jubilant HollisterStier | Washington, US | Handles fill and finish | 31 March 2021 |
| Siegfried | Hameln, Germany | Handles fill and finish | 4 May 2021 |
a
Novavax SEC third quarter, 2020 10‐Q filing.
Source: Constructed by the authors. Hyperlinks provide original sources.