Table 4.
Regions showing differences in grey matter volume between two groups
| Regions* | Gray matter volume, mm3,median (IQR) | MNI Coordinates | t-value | |||
|---|---|---|---|---|---|---|
| CSVD group (n = 24) | Control group(n = 21) | x | y | z | ||
| Right cerebellum | 1.067 (0.958,1.129) | 1.153 (1.029,1.240) | 17 | −57 | −50 | 8.912 |
| Left cerebellum | 1.136 (1.050,1.309) | 1.270 (1.197,1.458) | −14 | −63 | −51 | 8.169 |
| Right inferior frontal gyrus | 2.508 (2.228,2.782) | 2.497 (2.373,2.658) | 33 | 29 | −6 | 7.405 |
| Right thalamus | 4.117 (3.096,4.813) | 4.861 (4.407,5.354) | 17 | −18 | 15 | 6.500 |
| Left anterior cingulate cortex. | 4.119 (3.637,4.714) | 4.643 (4.241,4.908) | −6 | 6 | 35 | 6.492 |
| Right medial cingulate cortex | 3.858 (3.440,4.267) | 3.858 (3.758,4.142) | 9 | −9 | 39 | 6.155 |
| Right temporal pole | 1.394 (1.219,1.467) | 1.541 (1.395,1.662) | 36 | 3 | −21 | 6.165 |
| Right superior frontal gyrus | 10.320 (9.276,10.893) | 9.420 (9.075,9.732) | 24 | 45 | 23 | 5.781 |
| Right lingual gyrus | 5.929 (5.370,6.444) | 6.245 (5.814,6.397) | 14 | −83 | −6 | 5.594 |
| Left superior temporal gyrus | 5.190 (4.761,5.599) | 5.046 (4.651,5.551) | −45 | −24 | 5 | 5.429 |
*Locations of maximum effect(t > 4.8300; P < 0.00001) was shown. Regions were automatically labeled using the AnatomyToolbox atlas. x, y, and z = MNI coordinates in the left-right, anterior-posterior, and inferior-superior dimensions, respectively
Abbreviations: MNI Montreal Neurological Institute