Table 1.
Demographics | Co-morbidities | Vaccine | Onset of symptoms in relation to vaccination | Other vaccines | Type of IDP | Clinical presentation | CSF | NCS |
---|---|---|---|---|---|---|---|---|
Age: 51 Sex: Male Ethnicity: Caucasian |
NSTEMI*2020 | AZa | 2 weeks post 1st dose | Influenza vaccine 8 weeks post influenza vaccination |
GBSa | Nadir: at 2 weeks -lower back pain -Bifacial weakness -Dysphagia -Diplopia -Respiratory failure - Upper limb motor deficit - Progressive ascending lower limb sensorimotor deficit -Areflexia |
Albuminocytologic dissociation Protein: 0.70 WCC: 0 RBC: 0 Viral panel: negative Culture: no growth |
Absent ulnar and sural sensory reponses with slowed median sensory and motor NCV, prolonged distal motor latencies, absent F-waves. |
Age: 65 Sex: Female Ethnicity: Caucasian |
None | AZ | Onset: 1 week post 1st dose | Influenza vaccine 4 weeks post influenza vaccination |
GBS | Nadir: at 2 weeks -Lower Back Pain -Dysphagia - Diplopia -Respiratory failure -Progressive ascending upper limb and lower limb sensorimotor deficit -Areflexia |
Albuminocytologic dissociation Protein 2.51 g/L WCC: 5 RBS: 95 Viral panel - negative Culture – no growth |
Absent upper limb sensory responses with sural sparing, prolonged distal latencies, reduced amplitudes with temporal dispersion, slowed motor NCV, absent F-waves |
Age: 72 Sex: Male Ethnicity: Caucasian |
Idiopathic neuropathy | AZ | Onset: 3 weeks post 1st dose | Influenza vaccine 6 weeks post influenza vaccination |
CIDPa | Nadir: at 5 weeks -Lower back pain -Progressive ascending lower limb sensorimotor involvement -Upper limb motor deficit - areflexia |
Albuminocytologic dissociation Protein: 0.55 WCC: 0 RBC: 0 Viral Panel: not tested Culture: no growth |
Absent sensory responses, Prolonged distal motor, and F- minimum latencies, slowed motor NCV. |
Age: 66 Sex: Male Ethnicity: Caucasian |
Renal Cell Carcinoma Atrial Fibrillation Hypercholesterolemia |
AZ | 3 weeks post 1st dose | Influenza vaccine 8 weeks post influenza vaccine |
GBS | Nadir at 4 weeks: -lower back pain -Progressive ascending sensorimotor involvement -proximal lower limb weakness -areflexia |
Albuminocytologic dissociation Protein: 1.5 WCC 0 RBC 0 Culture: No growth Viral Panel: negative |
Absent median sensory responses with sural sparing, absent peroneal and tibal motor responses, prolonged median distal motor, and F- minimum latencies with slowed motor NCV. |
AZ = Oxford/AstraZeneca ChAdOx1 nCoV-19 COVID-19 vaccine, GBS = Guillain Barre Syndrome, CIDP = Chronic inflammatory demyelinating neuropathy, NCV = nerve conduction velocity.