Table 1.

PICO characteristics

Population	Intervention	Comparison	Outcome	Study design
Children (< 18 years) undergoing renal transplantation	Basiliximab, Tacrolimus, Prednisolone, Mycophenolate Mofetil, Azathioprine Valganciclovir Valaciclovir Co-trimoxazole	Any intervention compared with any other or no intervention	Mortality, Hospitalisations, Graft failure, Acute rejection, Infections, Growth.	Randomised controlled trials (RCT), non-randomised studies if adjusted for key confounders (age, health at baseline, co-morbidities).