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. 2021 Sep 3;12:723349. doi: 10.3389/fimmu.2021.723349

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Copyright © 2021 Strunz, Froehlich, Gernert, Schwaneck, Fleischer, Pecher, Tony, Henes and Schmalzing

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Age at aHSCT as a risk factor for developing an iAE. Comparison of the mean age at aHSCT as a risk factor between transplanted SSc patients with the onset of ES (+ES) and without the onset of ES (−ES) and patients with the onset of sAD (+sAD) and without sAD (−sAD). Older mean age at aHSCT was found to be associated with the development of ES. iAE, immunological adverse event; aHSCT, autologous hematopoietic stem cell transplantation; ES, engraftment syndrome; sAD, secondary autoimmune disease; SSc, systemic sclerosis. Error bars are given as SD.