Table 4.
Risk factor analysis for ES.
| Risk factor | ES | No ES | p |
|---|---|---|---|
| Mean age at aHSCT (years) | 52.45 ± 8.70 | 42.58 ± 11.63 | .0433 |
| Median of CD34+ cell dose (×106 cells/kg) | 3.330 (IQR, 1.263) | 3.195 (IQR, 1.338) | .6713 |
| Mean time to WBC recovery (days) | 12.43 ± 1.40 | 12.83 ± 2.37 | .6872 |
| Mean of max. leukocyte increase (n/µl) | 14,600 ± 5,543 | 10,640 ± 4,441 | .1482 |
| Risk factor | Odds ratio | 95% confidence interval | p |
| Male sex | 4.5 | 0.7297 to 27.75 | .1920 |
| Pulmonary manifestation | 9.00 | 0.4229 to 191.5 | .1150 |
| Cardiac manifestation | 40.11 | 1.885 to 853.6 | .0017 |
Risk factor analysis for engraftment syndrome. For metric scaled variables, means ± standard deviation or medians with interquartile range (IQR) are shown. Ordinal scaled variables are presented as odds ratio with 95% confidence interval. A higher mean age was found in the group with onset of engraftment syndrome. Cardiac involvement before HSCT was associated with the risk of developing ES. The other investigated variables showed no significant differences between the two groups.
ES, engraftment syndrome; WBC, white blood cell; HSCT, hematopoietic stem cell transplant.