Comparison 8. CFC‐BDP versus Placebo,on oral steroids: 400 mcg/d or less.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 FEV1 (% predicted)	1		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
1.1 Children	0		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
1.2 Adults	1		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
1.3 Children and Adults	0		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
2 Daily dose of oral prednisiolone (mg)	2	63	Mean Difference (IV, Fixed, 95% CI)	‐6.31 [‐8.68, ‐3.94]
2.1 Children	0	0	Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
2.2 Adults	2	63	Mean Difference (IV, Fixed, 95% CI)	‐6.31 [‐8.68, ‐3.94]
2.3 Children and Adults	0	0	Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
3 Reduction in daily dose of oral prednisolone (mg)	2	45	Mean Difference (IV, Fixed, 95% CI)	‐4.91 [‐5.88, ‐3.94]
3.1 Children	0	0	Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
3.2 Adults	2	45	Mean Difference (IV, Fixed, 95% CI)	‐4.91 [‐5.88, ‐3.94]
3.3 Children and Adults	0	0	Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
4 Daytime asthma symptom score	1		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
4.1 Children	0		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
4.2 Adults	1		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
4.3 Children and Adults	0		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
5 Night‐time asthma symptom score	1		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
5.1 Children	0		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
5.2 Adults	1		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
5.3 Children and Adults	0		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
6 Plasma cortisol (mmol/L)	1		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
6.1 Children	0		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
6.2 Adults	1		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
6.3 Children and Adults	0		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
7 Oropharyngeal side‐effects	1		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected
7.1 Children	0		Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
7.2 Adults	1		Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
7.3 Children and Adults	0		Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
8 Oropharyngeal Candidiasis (No. of patients)	1		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected
8.1 Children	0		Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
8.2 Adults	1		Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
8.3 Children and Adults	0		Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
9 Discontinuation of oral steroids (No. of patients)	4	152	Risk Ratio (M‐H, Random, 95% CI)	6.95 [2.79, 17.34]
9.1 Children	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
9.2 Adults	4	152	Risk Ratio (M‐H, Random, 95% CI)	6.95 [2.79, 17.34]
9.3 Children and Adults	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]